pco.edge 3.1 | scientific CMOS camera

sCMOS是新一代科學(xué)級成像芯片，zui低可探測到10個光子。sCMOS在普通CMOS的技術(shù)上進(jìn)行雙路讀出，雙路獨立放大，再分別進(jìn)行數(shù)模轉(zhuǎn)換，每路輸出11bit數(shù)字圖像，然后兩路11bit圖像重構(gòu)成16bit的高動態(tài)圖像。sCMOS繼承了CMOS的5T技術(shù)，同時在像元上增加了微透鏡，且采用片上CDS技術(shù)，減少了暗電流及讀出噪聲，split讀出機(jī)制更使sCMOS芯片同時具備了高靈敏、高動態(tài)、高分辨、高幀頻、低噪聲的特點。sCMOS還具體*的結(jié)構(gòu)設(shè)計，采用雙路讀出，雙路放大、雙路輸出后分別進(jìn)行數(shù)模轉(zhuǎn)換，然后重組成高動態(tài)范圍的圖像，因此具備了CMOS的高分辨率，高幀頻，還具備了高靈敏、低噪聲、高動態(tài)等特點。

特性描述：

• 雙路讀出，放大，A/D轉(zhuǎn)換
• 5T、微透鏡、片上CDS技術(shù)
• 超高分辨率5.5M
• 超高速度100fps
• 超高靈敏度和動態(tài)范圍16bit，88.6dB
• 超低讀出噪聲：<2erms

pco.edge 3.1 | scientific CMOS camera

rolling shutter readout modes - optimized for synchronization of microscopes and scanning applications

All pco.edge sCMOS cameras from the beginning feature a variety of precise synchronization modes,which are optimized for advanced microscopy imaging and scanning. The flexible frame and line triggers
with very low latency in combination with the free selectable readout modes can easily be combined to cover every modern microscopy situation
to name a few:

• lightsheet microscopy
• selective plane imaging microscopy (SPIM)
• structured illumination microscopy
• localizations microscopy(GSD, PALM, STORM, dSTORM)
• spinning disk confocal microscopy
• RESOLFT

For example, one mode is used in a lightsheet or SPIM application, the lower right rolling shutter operational mode “single top down” operation is convenient to properly synchronize the camera exposure with the scanner. On the other hand,if speed is required and a flash like exposure is applied the upper left mode “dual outside in” is used for localization microscopy techniques like GSD, PALM or STORM.

superior image quality
The new pco.edge camera (with scientific CMOS image sensor) features outstanding low read out noise of 1.1 electrons (e-) med. Even at maximum speed of 50 frames/s at full resolution of 2048 x 1536 pixel
the noise is 1.1 e- med. Moreover the pco.edge provides an excellent homogeneous pixel response to light (PRNU, photo response non-uniformity) and an excellent homogeneous dark signal pixel behaviour
(DSNU, dark signal non-uniformity), which is achieved by a sophisticated electronic circuit technology and firmware algorithms. The lower figure shows a comparison of a scientific grade CCD and the new pco.sCMOS image sensor under similar weak illumination conditions. This demonstrates the superiority of pco.sCMOS over CCD with regards to read out noise and dynamic, without any smear (the vertical lines in the CCD image).

型號	水平分辨率	垂直分辨率	數(shù)據(jù)接口	彩色/黑白	幀頻/行頻	產(chǎn)品手冊
pco.edge 3.1	2048	1536	USB 3.0	Color	50 fps
PCO.edge 4.2 LT	2048	2048	USB3.0	Color	40fps
PCO.edge 4.2	2048	2048	CameraLink/USB3.0	Color	100fps
PCO.edge 5.5	2560	2160	CameraLink/USB3.0	Color	100fps
PCO.edge Gold 4.2	2048	2048	USB3.0	Color	40fps
PCO.edge Gold 5.5	2560	2160	USB3.0	Color	32fps